Chicago White Sox at San Francisco Giants: Final Score & Recap

The Chicago White Sox erupted for all nine of their runs in a single devastating fourth inning to defeat the San Francisco Giants 9-4 at Oracle Park on May 22, 2026. The DiamondIQ model's estimate had the Giants entering with a 41 percent home win probability, but by the time the fourth inning concluded, that figure had collapsed to zero, reflecting just how thoroughly Chicago dismantled San Francisco in that one stretch of play.

The fourth inning was built on a series of compounding blows against Giants pitching, with Trevor McDonald absorbing the brunt of the damage. Andrew Benintendi's double was the single highest-leverage swing of the game, shifting win probability by plus 13.5 percent in Chicago's favor. Chase Meidroth followed with a walk that added another 11.2 percent, and Munetaka Murakami contributed twice in the frame, first being hit by a pitch for a 5.9 percent swing before doubling off Ryan Borucki for an additional 6.3 percent. Edgar Quero's fielder's choice off McDonald also moved the needle by 6.3 percent, illustrating how each successive plate appearance tightened the noose.

Murakami finished as the game's top offensive performer by WPA at plus 12.0 percent, paired with a RE24 of plus 2.8, underscoring his outsized contribution to run-scoring context. Meidroth checked in at plus 10.4 percent WPA and Benintendi at plus 9.4 percent, rounding out a trio that did the most damage in the decisive frame. On the mound, Davis Martin led Chicago's pitching staff with a plus 3.0 percent WPA, supported by Tyler Davis at plus 2.7 percent, as the White Sox held San Francisco to four runs spread across the fifth and sixth innings after the game had already been decided.