MLB Preview · June 25, 2026

Arizona Diamondbacks at St. Louis Cardinals: Prediction, Odds & Preview

AZ 49-47at STL 50-45·Busch Stadium·

DiamondIQ Model — Win Probability

AZ45.9%54.1%STL

The model leans STL (54.1%). DiamondIQ model v2: season records, home-field advantage, the starting-pitcher quality gap (PitchIQ), and a calibration adjustment fit and validated on four seasons of backtest — plus live game state once underway.

The Matchup

The Arizona Diamondbacks carry a 44-45 record into Busch Stadium on June 25 to face a Cardinals club that sits seven games above .500 at 47-40. The DiamondIQ model's estimate gives St. Louis a 55.4 percent win probability against Arizona's 44.6 percent, with home field and a meaningful starting-pitcher quality gap driving most of that lean. The model, which factors in team records, home field, and PitchIQ ratings but does not account for bullpens, lineups, or weather, favors the Cardinals in a moderate but not overwhelming fashion.

The pitching matchup is the clearest edge in this game. Zac Gallen takes the ball for Arizona carrying a 6.36 ERA, a 1.57 WHIP, and a 13.5 percent strikeout rate across 92.0 innings, and DiamondIQ's PitchIQ rates him at just 27 out of 100, a Fringe-tier designation. His four-seam fastball, thrown 37 percent of the time at 93.4 mph, is generating only 7 percent whiffs and a .397 wOBA against, which is a significant liability. His curveball has produced a .419 wOBA against as well, though his changeup stands out as a relative strength at .215 wOBA with 27 percent whiffs. Michael McGreevy has been considerably more effective, posting a 3.12 ERA and 1.11 WHIP in 95.1 innings. DiamondIQ rates him at 37 out of 100, Below Average, but his sinker and changeup combination is limiting damage, with the sinker holding opponents to a .242 wOBA and the changeup at .246 with 27 percent whiffs. There is a real quality gap between these two.

One notable condition at Busch Stadium is the forecast of 101 degrees at first pitch with an 11 mph wind blowing out to center field. While the DiamondIQ model does not incorporate weather, that combination could create a more offense-friendly environment than the pitching lines might otherwise suggest. From a bullpen standpoint, Arizona's BullpenIQ sits at 53 out of 100 with four relievers carrying heavy workloads and three considered likely unavailable, which could place added stress on Gallen to eat innings. St. Louis's bullpen grades at 42 out of 100 with five heavy-usage arms, so neither side has a fresh relief corps to rely on. The thing to watch is how deep McGreevy can go, because if he exits early, the Cardinals are leaning on a taxed bullpen against a team that cannot afford to fall behind a starter of his caliber.

Analysis generated by DiamondIQ's model.

Probable Pitchers

AZ
ERA
6.34
WHIP
1.56
K%
13.9
BB%
7.0
K/9
5.60
IP
98.0
Arsenal
Four-Seam 37% · 93mphSlider 22% · 89mphCurveball 19% · 82mphChangeup 18% · 87mphSinker 5% · 93mph
STL
ERA
3.01
WHIP
1.10
K%
16.5
BB%
5.7
K/9
5.84
IP
101.2
Arsenal
Four-Seam 26% · 92mphChangeup 20% · 87mphSinker 17% · 91mphCutter 12% · 87mphCurveball 11% · 78mph

Forecast at First Pitch

☀️97°FClear
Wind 14 mph W · out to CF
Precip 14%

Injured List

AZ
Jordan Lawlar (LF)Injured 10-Day
Tommy Troy (LF)Injured 10-Day
Michael Soroka (P)Injured 15-Day
Zac Gallen (P)Injured 15-Day
A.J. Puk (P)Injured 60-Day
Andrew Saalfrank (P)Injured 60-Day
STL
Max Rajcic (P)Injured 60-Day
Ramón Urías (3B)Injured 60-Day
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